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In the UPS, proteins are selectively marked by ubiquitination, the covalent addition of ubiquitin (Ub) molecules to lysine residues, which signals and targets the protein for proteolytic degradation by the 26S proteasome

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Once reconstituted in water, refrigerate the solution at 2 to 8 °C, use it within a validated window, and keep it away from strong reducing agents that can disturb the copper