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All five received a favorable, non-binding recommendation for the 503A bulks list — TB-500 8–6 with 1 abstention, KPV 8–6 with 1 abstention, MOTS-c 7–5 with 2 abstentions, semax 8–5, and epitalon 7–4 — and all five remain unapproved drugs pending FDA rulemaking

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Research describes effects on fibroblast proliferation, collagen organisation, and blood vessel formation (angiogenesis) through mechanisms involving VEGF upregulation and FAK-paxillin pathway activation