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Kraus and colleagues showed in Nature in 2014 that Nnmt is the most strongly reciprocally regulated gene in adipose tissue between Glut4-knockout and Glut4-overexpressing mice, and that NNMT expression rises in white adipose tissue and liver of obese and diabetic mice

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While the former is excellent for dissolving or diluting drugs, the latter, with its salt concentration mirroring that of bodily fluids, is a champ for rehydration and electrolyte balance restoration