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A study indicates that a drug delivery system based on curcumin will be proposed for the treatment of ALS (Tripodo et al., 2015) but others indicate that the use of curcumin as therapy in ALS has disadvantages: chemical instability and low oral bioavailability and water solubility rate (Rakotoarisoa and Angelova, 2018) (Table 1)

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Understanding the financial commitment upfront helps with planning and prevents interrupted protocols due to budget constraints