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Finally, the acute administration of high doses of MPH can cause oxidative and inflammatory changes in brain cells and induce neurodegeneration in the hippocampus and cerebral cortex of adult rats [137]

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02 Peptide Structure–Activity Relationships Because of its defined pentapeptide structure Ipamorelin is suitable for use in structure–activity relationship (SAR) research and experimental comparisons between Ipamorelin and other compounds which have a similar structure can help to show how specific modifications to residues affect molecular recognition and receptor-associated activity