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Peptides in this class act at different levels of this axis: GHRH analogs (CJC-1295) stimulate the pulsatile release of GH, GHRP secretagogues (ipamorelin, GHRP-2, GHRP-6) activate ghrelin receptors, and tesamorelin—the only peptide in this class approved by the FDA—increases endogenous GH without supraphysiological effects