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Practical take For clinicians, this reinforces a more nuanced approach: Match the drug to the patient profile Look beyond average weight loss alone Consider tolerability, adherence, comorbidities, access, and long-term strategy The obesity pipeline is getting deeper—and that is good news for patients
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In addition, the variation in the transient receptor potential vanilloid 1 (TRPV1) gene has also been shown to be associated with NPP (32)