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In addition, histopathological and immunohistochemical assessments were performed to evaluate tissue architecture, inflammatory infiltration, collagen deposition, and the expression of VEGF, eNOS, IL-6, and caspase-3

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Angiotensin-converting enzyme 2 (ACE2) is a protease that, with its companion the angiotensin-converting enzyme ACE, takes part in the renin-angiotensin system (RAS)