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Note that the frequently quoted figure of roughly 4,000 genes is an extrapolation from Connectivity Map analysis rather than a direct count, so it is worth citing as such

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FOXO4-DRI counteracts chemotherapy-induced senescence and loss of liver function Given the potency of FOXO4-DRI against senescence in vitro , we wondered whether FOXO4-DRI could be of therapeutic use against senescence-related pathologies